Keppra and Headaches

Keppra is one of the newer kids on the block in anti-seizure medications. Although it does not carry the indication for headaches, none the less many anti-seizure drugs are used in recurring headaches.

Keppra is showing some success in treating chronic migraines. Although not as effective as topamax and depakote, it may be effective if the other two are not. Unlike, Topamax, Depakote and Zonagran, Keppra for headaches has no drug-drug interactions. It also has a low side effect profile.

Also, unlike the others, I have found that if people are going to respond to this drug, it is usually at higher doses. In fact, they have to take anti-seizure doses. However, the drug is well tolerated to this is not much of a problem.

SIDE EFFECTS: The most common side effect I hear is mild dizziness. This tends to wear off. A few patients have had some nausea and have had to discontinue the medication.

You should not take this medication if you are pregnant unless your doctor deems it necessary.

Overall Keppra and headaches seem to be a good match if other anti-seizure drugs have failed.

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