Depakote MigraineIs the depakote migraine connection best for you? Depakote and headache actually makes for a good combination. Depakote is an older anti-seizure drug that is very effective for treating recurring headaches. This is a drug that we consider to be one of the best headache medications if you are having 2-3 headaches per week or more than one disabling headache per month. Interestingly, this medication has side effects which are actually BENEFICIAL to headache patients. One of the side effects is sedation. Great you say! If you take Depakote before bedtime, not only can it help get you to sleep, but it also treats the headaches by reducing the frequency and severity of them. I have seen Depakote be very effective in patients who have chronic daily headaches, and especially effective in people who have migraines. This anti-seizure drug is taken in low doses to treat headaches. What you are looking for is a reduction in the frequency and severity of your headaches. The dose will be adjusted until you are stable (1 headache per month or so). Keep in mind this is also a great drug if you suffer from
depression and migraine.
Some patients are afraid of Depakote having read that it causes weight gain. While this happens in less than 10% of patients, it is reversible when the medication is stopped. You should probably not take Depakote if you have a history of liver disease, are pregnant or have a condition known as PCOS(poly cystic ovarian syndrome). If you think the combination of depakote migraine might work for you, speak to your provider.
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